IRG 1, Reconfigurable Porous Nanoparticle Networks, addresses multifunctional, reconfigurable networks of nanoparticles, polymers, and organic molecules that respond to a range of external stimuli. Fundamental principles are elucidated for understanding and controlling the assembly and reconfiguration of nanoparticles connected by molecular linkers, with theoretical and experimental efforts combining to create unique optical, chemical, or biological materials functionality. Research advances in this IRG are expected to enable responsive, reconfigurable materials based on integration of nanoparticles and macromolecules for applications in electronics, energy storage, photonics, and biology.